Publications

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1. ​Joseph N, Shrestha S, Sassmannshausen I, Mizkus S, Chumala P, Sivakumar B, Baiju V, Ahmed S, Rees H, Katselis GS, Krishnan A*. An experimental method for perineural invasion simulating natural invasion of cancer cells into nerves (currently available to view in bioRxviv: doi: https://doi.org/10.1101/2025.03.21.644644).

2. Sivakumar B, Hammond C, Martinez V, Joseph N, John VJ, Kumar A, Krishnan A*. Schwann cells modified to secrete MANF is a potential cellular therapy for peripheral nerve regeneration (currently available to view in bioRxviv: doi: https://doi.org/10.1101/2025.03.14.642904)

3. Walke P, Price JDW, Vizeacoumar FS, Joseph N, Maranda V, Chowdhury B, Patel J, Zhang Y, Dong H, New L, Ganapathysamy A, Gong LH, Elhasasna H, Bhanumathy KK, Wu Y, Freywald A*, Krishnan A*, Vizeacoumar F* (*Corresponding authors). A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer (Accepted in Oncogene 2025).

4. Cunningham CE, Vizeacoumar FS, Zhang Y, Kyrylenko L, Gao P, Maranda V, Dong H, Price JDW, Ganapathysamy A, Hari R, Denomy C, Both S, Wagner K, Wu Y, Khan F, Mosley S, Chen A, Katrii T, Zoller BGE, Rajamanickam K, Walke P, Gong L, Patel H, Lazell-Wright M, Morales AM, Bhanumathy KK, Elhasasna H, Dahiya R, Abuhussein O, Dmitriev A, Freywald T, Munhoz EP, Krishnan A, Ruppin E, Datla JR, Yadav S, Wu Y, Baker K, Empting M, Kiemer AK, Freywald A, Vizeacoumar FJ. Identification of targetable vulnerabilities of PLK-1 overexpressing cancers by synthetic dosage lethality (Accepted in Cell Genomics 2025).

5. ​Poitras TM, Komirishetty P, Areti A, Larouche M, Krishnan A, Chandrasekhar A, Munchrath E, Zochodne DW. Manipulation of the Myc Interactome to Enhance Nerve Regeneration in a Murine Model. Ann Neurol. 2024 May 31. doi: 10.1002/ana.26950.

6. Krishnan A*, Verge VMK, Zochodne DW (Book Chapter). Hallmarks of peripheral nerve injury and regeneration. Handb Clin Neurol. 2024; 201: 1-17.

7. Sivakumar B, Krishnan A*. Mesencephalic astrocyte-derived neurotrophic factor (MANF): An emerging therapeutic target for neurodegenerative disorders. Cells. 2023; 12(7): 1032

8. Bautista M, Katselis G, Chowdhury B, Chumala P, Mahendra R, Desai P, Hall J, Kalyaanamoorthy S, Krishnan A*. Comparative proteomics analysis of growth-primed adult dorsal root ganglia reveals key molecular mediators for peripheral nerve regeneration. eNeuro 2023 Jan 5;10 (1):0168-22.2022

9. Krishnan A, Areti A, Komirishetty P, Chandrasekhar A, Cheng C, Zochodne DW. Survival of compromised adult sensory neurons involves macrovesicular formation. Cell Death Discov. 2022 Nov 24;8(1):462.

10. Krishnan, A* (Book Chapter). Tumor-Nerve Interface: An Emerging Therapeutic Intervention Point for Solid Cancers. In: Interdisciplinary Cancer Research (2022). Springer, Cham. https://doi.org/10.1007/16833_2022_35

11. Krishnan, A* (Book Chapter). Neuroimmune Crosstalk in the Tumor Microenvironment. In: Rezaei, N. (eds) Handbook of Cancer and Immunology (2022). Springer, Cham. https://doi.org/10.1007/978-3-030-80962-1_92-1

12. Elhasasna H, Khan R, Bhanumathy KK, Vizeacoumar FS, Walke P, Bautista M, Dahiya DK, Miranda V, Patel H, Balagopal A, Alli N, Krishnan A, Freywald A, Vizeacoumar FJ. (2022). A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers. Cells. 2022 Jul 20;11(14):2246.

13. Bautista, M.,Krishnan, A*. Self-renewal of peripheral nerve resident macrophage: Does it represent a unique activation status?, Neural Regen Res. 2022 May;17(5):999-1000.

14. Dwivedi S, Bautista M, Shrestha S, Elhasasna H, Chaphekar T, Vizeacoumar FS, Krishnan A*. Sympathetic signaling facilitates progression of neuroendocrine prostate cancer. Cell Death Discov. 2021 Nov 22;7(1):364. 

15. Krishnan A, Dwivedi S, Chandrasekhar A, Areti A, Zochodne D. In vitro priming response in dorsal root ganglia partially mimics injury-driven pre-conditioning response and reprograms neurons for enhanced outgrowth. Mol Cell Neurosci. 2021 Jan;110:103573.

16. Dwivedi S, Krishnan A*. Neural invasion: a scenic trail for the nervous tumor and hidden therapeutic opportunity. Am J Cancer Res. 2020;10(8):2258-2270.

17. Bautista M and Krishnan A*. The Autonomic Regulation of Tumor Growth and the Missing Links. Front Oncol. 2020 May 13; 10:744.

18. Krishnan A, Bhavanam S, Zochodne DW. An intimate role for adult dorsal root ganglia resident cycling cells in the generation of local macrophages and satellite glial cells. J Neuropathol Exp Neurol. 2018 Oct 1;77(10):929-941). 

19. Asahchop EL, Branton WG, Krishnan A, Chen PA, Yang D, Kong L, Zochodne DW, Brew BJ, Gill MJ, Power C. HIV-associated sensory polyneuropathy and neuronal injury are associated with miRNA-455-3p induction. JCI Insight.2018 Dec 6;3(23).

20. Christie KJ #, Krishnan A #, Martinez JA, Purdy K, Singh B, Eaton S, Zochodne D. Enhancing adult Nerve Regeneration through the knockdown of Retinoblastoma Protein.  Nat Commun. 2014 Apr 22; 5:3670 (#equal contribution). 

21. Singh B, Singh V#, Krishnan A#, Koshy K, Martinez J, Cheng C, Almiquist C, Zochodne DW. Regeneration of diabetic axons is enhanced by selective knockdown of the PTEN gene. Brain. 2014 Apr; 137(Pt 4):1051-67. (#equal contribution)